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GenScript Monorab™ Rabbit Anti-Humanized Vhh Antibody, Mab; 200ul
List Price $240.00 Your Price $240.00
GenScript Monorab™ Rabbit Anti-Humanized Vhh Antibody, Mab200ul - GSCRPT (Additional S&H or Hazmat Fees May Apply)
NETA PART: GSCRPT-A02165-200
MFG.PART: A02165-200
UNSPSC: 12352203
Manufacturer: GenScript USA Inc
Overview
| Specificity | The product is specific for Humanized VHH antibodies and Camelid (Llama,Alpaca, and Camel) heavy chain antibodies (IgG2 & 3), but does notrecognize the camelid conventional antibody (IgG1). |
| Host Species | Rabbit |
| Immunogen | VHH antibody |
| Species Reactivity | No cross-reactivity with mouse, rat, rabbit, or goat immunoglobulins. |
| Conjugate | Unconjugated |
Applications
| Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. | |||||||||
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Properties
| Form | Liquid |
| Storage Buffer | Supplied in PBS (pH 7.2) with 0.02% sodium azide and 50% glycerol. |
| Concentration | 0.5 mg/mL |
| Storage Instructions | Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. |
| Purification | Protein A affinity column |
| Isotype | Rabbit IgG |
| Clonality | Monoclonal |
| Clone ID | 45H8 |
| Note | GenScript can customize this product per customers request including product size, buffer components, etc. |
Background
| Target Background | A camelid single-domain antibody (sdAb, called Nanobody by Ablynx) is apeptide chain about 110 amino acids long comprising one variable domain of a heavy-chain antibody (VHH fragment). Like awhole antibody, a single-domain antibody is able to bind selectively to aspecific antigen. Such antibodies allow a broad range of applications inbiotechnical as well as therapeutic fields due to their small size, simpleproduction, and high affinity. However, their sequences may increase the riskof immunogenicity and cause anti-drug antibody (ADA) development in humans, andthus, sdAbs are routinely humanized during development. |
| Synonyms | Rabbit anti-Humanized VHH, single-domain antibody monoclonal antibody(Min X Ms, Rt, Rb, Gt). |
| Reference | 1. Immunogenicity and humanization of single-domain antibodies. 2. Properties, production, and applications of camelid single-domain antibody fragments. |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
| SKU | GSCRPT-A02165-200 |
|---|---|
| Supplier Part Number | A02165-200 |
| UM | EA |
| UNSPSC | 12352203 |
| Manufacturer | GenScript USA Inc |
| Temperature | Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. |
| ProductLine | GSCRPT |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 7 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |