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Key Specifications Table
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| R, M, Gp | WB | Rb | Serum | Polyclonal Antibody |
| Description | |
|---|---|
| Catalogue Number | 07-1406 |
| Replaces | AB1348 |
| Description | Anti-GLUT-5 Antibody, a.a. 490-502 |
| Alternate Names |
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| Background Information | A cytochalasin B-sensitive carrier located in the membrane, GLUT-5 appears to be primarily functional as a fructose transporter. It is expressed in the small intestine, and is also found in the skeletal muscle, kidney and adipose tissue but at significantly reduced levels. |
| Product Information | |
|---|---|
| Format | Serum |
| Control |
|
| Presentation | Liquid containing 0.05% sodium azide. |
| Quality Level | MQ100 |
| Applications | |
|---|---|
| Application | Anti-GLUT-5 Antibody, a.a. 490-502 detects level of GLUT-5 & has been published & validated for use in WB. |
| Key Applications |
|
| Biological Information | |
|---|---|
| Immunogen | Synthetic peptide corresponding to the C-terminus of rat GLUT-5 (aa 490-502) coupled to KLH. The immunogen sequence used is only 53% conserved in mouse. |
| Epitope | C-terminus |
| Host | Rabbit |
| Specificity | Recognizes GLUT-5. |
| Species Reactivity |
|
| Antibody Type | Polyclonal Antibody |
| Entrez Gene Number |
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| Gene Symbol |
|
| Purification Method | Unpurified rabbit serum |
| UniProt Number |
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| UniProt Summary | FUNCTION: Cytochalasin B-sensitive carrier. Seems to function primarily as a fructose transporter. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue. INDUCTION: By forskolin (in Caco-2 cells). SEQUENCE SIMILARITIES: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. [View classification] MASS SPECTROMETRY: Molecular mass is 54973.98 Da from positions 1 - 501. Determined by MALDI. SEQUENCE CAUTION: The sequence AAB60641.1 differs from that shown. Reason: Erroneous gene model prediction. |
| Molecular Weight | Approx. 54 kDa |
| Product Usage Statements | |
|---|---|
| Quality Assurance | Evaluated by Western Blot in Mouse kidney lysate. Western Blot Analysis: A 1:1000 dilution of this antibody detected GLUT-5 in 10 µg of mouse kidney lysates. |
| Usage Statement |
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| Storage and Shipping Information | |
|---|---|
| Storage Conditions | Store at -20°C in undiluted aliquots for up to 1 year from date of receipt. Avoid repeated freeze-thaw cycles. |
| Packaging Information | |
|---|---|
| Material Size | 50 µL |