The store will not work correctly when cookies are disabled.
We use cookies to make your experience better.To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
NETA ALERT: Due to inclement weather our offices are closed today, Monday Feb. 23. We will not be shipping orders.
Millipore Detect Phosphothreonine-Proline Using This Anti-Phosphothreonine-Proline Antibody Validated For Use In Wb. - Mill (Additional S&H or Hazmat Fees May Apply)
Phosphothreonine-Proline, along with similar motifs involving serine/threonine residues preceding proline undergoing phosphorylation, has critical roles in the moderation of various cellular processes, protein function, and kinases through proline-directed phosphorylation. The deregulation of proline-directed phosphorylation is known to be a factor in diseases such as cancer and Alzheimer’s neurodegeneration.
Product Information
Format
Affinity Purified
Control
Calyculin treated Jurkat cell lysate
Presentation
Liquid in TBS with 0.05% sodium azide and 50% glycerol.
Quality Level
MQ100
Applications
Application
Detect Phosphothreonine-Proline using this Anti-Phosphothreonine-Proline Antibody validated for use in WB.
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Rabbit
Specificity
Recognizes the phosphorylated phothreonine-proline motif, which is the site of phosphorylation of many proline-directed protein kinase such MAPK and cyclin-dependent protein kinases. Also recognizes the phosphoserine-proline motif to a similar degree.
Species Reactivity
Human
Mouse
Rat
Antibody Type
Polyclonal Antibody
Purification Method
Affinity Purfied
Product Usage Statements
Quality Assurance
Evaluated by Western Blot in Calyculin treated Jurkat cell lysate. Western Blot Analysis: 1:500 dilution of this lot detected phosphorylated proteins on 10 μg of calyculin treated Jurkat lysates.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
Maintain at -20°C in undiluted aliquots for up to 12 months from date of receipt. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
