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Millipore Active, N-Terminal His6-Tagged, Recombinant, Human Kdr Amino Acids 790-End, For Use In Kinase Assays. - Mill (Additional S&H or Hazmat Fees May Apply)
human KDR expressed by baculovirus in Sf21 insect cells
Product Information
Quality Level
MQ100
Applications
Application
Active, N-terminal His6-tagged, recombinant, human KDR amino acids 790-end, for use in Kinase Assays.
Key Applications
Kinase Assay
Biological Information
Source
N-terminal His6-tagged, recombinant, human KDR amino acids 790-end
Specific Activity
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
NM_002253.1
Gene Symbol
KDR
VEGFR-2
VEGFR2
CD309
FLK1
VEGFR
Protein Target
KDR
Purification Method
Ni2+/NTA-agarose
Target Sub-Family
TK
UniProt Number
P35968
UniProt Summary
FUNCTION: SwissProt: P35968 # Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposis sarcoma lesions. SIZE: 1356 amino acids; 151527 Da SUBUNIT: Interacts with SHB upon VEGF activation. Interacts with HIV-1 Tat. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. SIMILARITY: SwissProt: P35968 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. & Contains 7 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 protein kinase domain.
Molecular Weight
67.9kDa
Product Usage Statements
Quality Assurance
routinely evaluated by phosphorylation of myelin basic protein (MBP)
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
