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Key Specifications Table
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| H | ELISA, WB | Rb | Purified | Polyclonal Antibody |
| Description | |
|---|---|
| Catalogue Number | AB10627 |
| Brand Family | Chemicon® |
| Trade Name |
|
| Description | Anti-Omentin Antibody |
| Background Information | A calcium-dependent lectin with affinity for furanosides, such as galactofuranosyl in bacterial arabinogalactans. 30kD of apparent molecular weight of Omentin migrate at 40-kD under reducing conditions due to glycosylation. Omentin, a novel visceral fat depot-specific secretory protein, enhance insulin-stimulated glucose transport in subcutaneous as well as omental adipocytes and may therefore be implicated in the pathogenesis of obesity. |
| Product Information | |
|---|---|
| Format | Purified |
| Presentation | Liquid in PBS, pH7.4. Contains no preservatives. |
| Quality Level | MQ100 |
| Applications | |
|---|---|
| Application | Anti-Omentin Antibody detects level of Omentin & has been published & validated for use in ELISA & WB. |
| Key Applications |
|
| Application Notes | Western blot: 1:2,000-1:5,000 using ECL. Reacted with the ~40kDa Omentin His-tagged protein. Suggested blocking and dilution buffer is PBST with 0.05% Tween-20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature. ELISA, direct and indirect: 1:2,000-1:5,000. |
| Biological Information | |
|---|---|
| Immunogen | Synthetic peptide: TVGDRWSSQQGSKADYPEGDG, corresponding to amino acids 95-115 of Human Omentin. |
| Epitope | Amino acids 95-115 of Human Omentin. |
| Concentration | Please refer to the Certificate of Analysis for the lot-specific concentration. |
| Host | Rabbit |
| Specificity | Recognizes Omentin in western blotting. |
| Species Reactivity |
|
| Antibody Type | Polyclonal Antibody |
| Entrez Gene Number |
|
| Gene Symbol |
|
| Purification Method | Protein A Purfied |
| UniProt Number |
|
| UniProt Summary | FUNCTION: SwissProt: Q8WWA0 # May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism. SIZE: 313 amino acids; 34962 Da SUBUNIT: Homotrimer; disulfide-linked. SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor, GPI-anchor. Secreted. TISSUE SPECIFICITY: Specifically expressed in the small intestine. Also found the heart, testis, colon, salivary gland, skeletal muscle, pancreas and thyroid; and to a lesser degree in the uterus, spleen, prostate, lymph node and thymus. DEVELOPMENTAL STAGE: Found in fetal small intestine and thymus. PTM: N-glycosylated. SIMILARITY: SwissProt: Q8WWA0 ## Contains 1 fibrinogen C-terminal domain. |
| Molecular Weight | 30-40 kDa |
| Product Usage Statements | |
|---|---|
| Usage Statement |
|
| Storage and Shipping Information | |
|---|---|
| Storage Conditions | Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. |
| Packaging Information | |
|---|---|
| Material Size | 100 µg |