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Millipore Anti-Map2 Antibody Detects Level Of Map2 & Has Been Published & Validated For Use In Ic, Ih. - Mill (Additional S&H or Hazmat Fees May Apply)
Affinity purified chicken immunoglobulin. Two different antibodies were combined to make this product. Liquid in PBS, pH 7.2 with 0.02% sodium azide.
Quality Level
MQ100
Applications
Application
Anti-MAP2 Antibody detects level of MAP2 & has been published & validated for use in IC, IH.
Key Applications
Immunocytochemistry
Immunohistochemistry
Application Notes
Immunohistochemistry: 1:1000-1:2,000 using 2% paraformaldehyde fixed tissue.
Immunocytochemistry: 1:1000-1:2,000 using 2% paraformaldehyde fixed cells.
Optimal working dilutions must be determined by end user.
Biological Information
Immunogen
Synthetic peptides corresponding to different regions of the human/mouse MAP2 protein.
Host
Chicken
Specificity
MAP2 [Microtubule associated protein 2]
Species Reactivity
Mouse
Species Reactivity Note
Other species have not yet been tested. It is expected that the antibody will also react with human due to immunogen sequence similarity.
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NM_001039538.1
NM_002374.3
NM_031845.2
NM_031847.2
Entrez Gene Summary
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isforms have been described.
Gene Symbol
MAP2
MAP2B
MAP-2
MAP2C
DKFZp686I2148
MAP2A
Purification Method
ImmunoAffinity Purified
UniProt Number
P11137
UniProt Summary
FUNCTION: SwissProt: P11137 # The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. SIZE: 1827 amino acids; 199539 Da PTM: MAP2A/c is phosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR. SIMILARITY: SwissProt: P11137 ## Contains 3 Tau/MAP repeats.
Product Usage Statements
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.
