The store will not work correctly when cookies are disabled.
We use cookies to make your experience better.To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies.Learn about our cookie policy.
Millipore Anti-Beta Iii Tubulin, Cy3 Conjugate Antibody
Millipore Anti-Beta Iii Tubulin, Cy3 Conjugate Antibody
List Price$692.64Your Price$692.64
Millipore This Anti-Beta Iii Tubulin, Cy3 Conjugate Antibody Is Validated For Use In Icc For The Detection Of Beta Iii Tubulin. - Mill (Additional S&H or Hazmat Fees May Apply)
Tubulin is one of several members of a small family of globular proteins which polymerize to form cytoskeletal structures called microtubules. The most common members of the tubulin family are α-tubulin and β-tubulin. Tubulin dimers, typically composed of α- and β-tubulin subunits, assemble onto microtubules forming large polymers. β-III tubulin is a unique microtubule subunit that is found expressed almost exclusively in neurons. Due to the unique expression pattern of β-III tubulin it is often utilized as a marker to identify neuronal cells from other brain cells such as glia which do not express it. β-III tubulin also serves as a cytoarchitectural marker since it is primarily found within neurite extensions.
Product Information
Format
Cy3
Control
Rat E18 cortex cells
Presentation
Purified rabbit polyclonal conjugated to Cy3 in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Quality Level
MQ100
Applications
Application
This Anti-Beta III Tubulin, Cy3 Conjugate Antibody is validated for use in ICC for the detection of Beta III Tubulin.
Key Applications
Immunocytochemistry
Biological Information
Immunogen
Synthetic linear peptide corresponding to human Beta III Tubulin.
Host
Rabbit
Species Reactivity
Human
Mouse
Rat
Species Reactivity Note
Demonstrated to react with Rat. Predicted to react with Human and Mouse based on 100% sequence homology.
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NP_006077
Gene Symbol
TUBB3
TUBB4
MC1R
beta-4
Purification Method
Affinity Purfied
UniProt Number
Q13509
UniProt Summary
FUNCTION: SwissProt: Q13509 # Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. SIZE: 450 amino acids; 50433 Da SUBUNIT: Dimer of alpha and beta chains. DOMAIN:SwissProt: Q13509 The highly acidic C-terminal region may bind cations such as calcium. SIMILARITY: Belongs to the tubulin family.
Molecular Weight
50 kDa calculated
Product Usage Statements
Quality Assurance
Evaluated by Immunocytochemistry in rat E18 cortex cells. Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected Beta III Tubulin in rat E18 cortex cells.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
