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Millipore This Anti-Parvalbumin Antibody Is Validated For Use In Ih(P) For The Detection Of Parvalbumin. - Mill (Additional S&H or Hazmat Fees May Apply)
This Anti-Parvalbumin Antibody is validated for use in IH(P) for the detection of Parvalbumin.
Key Applications
Immunohistochemistry (Paraffin)
Application Notes
Immunohistochemistry: 1:100 on paraffin embedded, 10% neutral Buffered Formalin fixed human cerebellum tissue. Suggested pretreatment is HIER (Heat Induced Epitope Retrieval) using Citrate buffer, pH 6.0. Detection system was the IHC-Select HRP-DAB system.
Biological Information
Immunogen
Synthetic peptide.
Host
Rabbit
Specificity
Parvalbumin. Immunoreactivity is seen primarily in Purkinje cells. Immunostaining is completely eliminated when the antibody is incubated with the immunogen peptide prior to staining.
Species Reactivity
Human
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NM_002854.2
Entrez Gene Summary
The protein encoded by this gene is a high affinity calcium ion-binding protein that is structurally and functionally similar to calmodulin and troponin C. The encoded protein is thought to be involved in muscle relaxation.
Gene Symbol
PVALB
parvalbumin
D22S749
MGC116759
Purification Method
Serum
UniProt Number
P20472
UniProt Summary
FUNCTION: SwissProt: P20472 # In muscle, the calcium-binding protein parvalbumin is thought to be involved in muscle relaxation. SIZE: 110 amino acids; 12059 Da SIMILARITY: SwissProt: P20472 ## Belongs to the parvalbumin family. & Contains 2 EF-hand domains. MISCELLANEOUS: This protein binds two calcium ions.
Product Usage Statements
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
