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Key Specifications Table
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| H, Ht, M, R, Rb, Sh | DB, ICC, IH(P), RIA | Rb | Serum | Polyclonal Antibody |
| Description | |
|---|---|
| Catalogue Number | AB911 |
| Brand Family | Chemicon® |
| Trade Name |
|
| Description | Anti-Oxytocin Antibody |
| Product Information | |
|---|---|
| Format | Serum |
| Control |
|
| Presentation | Neat rabbit antisera. Liquid. Contains no preservative. |
| Quality Level | MQ100 |
| Applications | |
|---|---|
| Application | Anti-Oxytocin Antibody is an antibody against Oxytocin for use in DB, IC, IH(P), RIA. |
| Key Applications |
|
| Application Notes | Immunohistochemistry: 1:5,000-1:10,000 (18-24 hour incubation) on formalin, Bouins or Zambonis fixed tissue. Will react on paraffin embedded tissue. Immunocytochemistry: 1:10,000 on fetal rat neurons. Dot Blot: 1:1000 RIA Optimal working dilutions must be determined by the end user. |
| Biological Information | |
|---|---|
| Immunogen | Synthetic oxytocin (Sigma) conjugated to thyroglobulin. |
| Concentration | Please refer to the Certificate of Analysis for the lot-specific concentration. |
| Host | Rabbit |
| Specificity | Recognizes Oxytocin. Less than 1% cross-reactivity with arginine vasopressin. |
| Species Reactivity |
|
| Antibody Type | Polyclonal Antibody |
| Entrez Gene Number |
|
| Entrez Gene Summary | There are two proteins encoded by this gene, oxytocin and neurophysin I. Oxytocin is posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. |
| Gene Symbol |
|
| Purification Method | Unpurified |
| UniProt Number |
|
| UniProt Summary | FUNCTION: SwissProt: P01178 # Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland. SIZE: 125 amino acids; 12722 Da SUBCELLULAR LOCATION: Secreted. SIMILARITY: SwissProt: P01178 ## Belongs to the vasopressin/oxytocin family. |
| Product Usage Statements | |
|---|---|
| Usage Statement |
|
| Storage and Shipping Information | |
|---|---|
| Storage Conditions | Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
| Packaging Information | |
|---|---|
| Material Size | 100 µL |