The store will not work correctly when cookies are disabled.
We use cookies to make your experience better.To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies.Learn about our cookie policy.
Millipore This Anti-Clathrin Light Chain Antibody Is Validated For Use In Wb For The Detection Of Clathrin Light Chain. - Mill (Additional S&H or Hazmat Fees May Apply)
This Anti-Clathrin Light Chain Antibody is validated for use in WB for the detection of Clathrin Light Chain.
Key Applications
Western Blotting
Application Notes
Western blot: 1:50,000-1:100,000 on rat brain extracts.
Optimal working dilutions must be determined by end user.
Biological Information
Immunogen
Synthetic peptide
Host
Rabbit
Specificity
Clathrin light chain a and b variants (CLC). By Western blot the antibody recognizes a doublet at ~35-40 kDa on rat brain extracts.
Species Reactivity
Human
Rat
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NM_001076677.1
NM_001833.2
NM_007096.2
Entrez Gene Summary
Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants.
Gene Symbol
CLTA
LCA
Lca
UniProt Number
P09496
P09497
UniProt Summary
FUNCTION: SwissProt: P09497 # Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. SIZE: 229 amino acids; 25190 Da SUBUNIT: Clathrin coats are formed from molecules containing 3 heavy chains and 3 light chains. SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane; Cytoplasmic side. Membrane, coated pit; Cytoplasmic side. Note=Cytoplasmic face of coated pits and vesicles.
Molecular Weight
~35-40 kDa
Product Usage Statements
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
