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Millipore Detect No66 Using This Rabbit Polyclonal Antibody, Anti-Histone Lysine Demethylase No66 Antibody Validated For Use In Western Blotting. - Mill (Additional S&H or Hazmat Fees May Apply)
Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66
60S ribosomal protein L8 histidine hydroxylase
Histone lysine demethylase NO66
Myc-associated protein with JmjC domain
Nucleolar protein 66
hsNO66
Ribosomal oxygenase NO66
ROX
NO66
Background Information
NO66 is a lysine-specific demethylase that removes methyl groups from histone H3 at lysine 4 and lysine 36. This enzyme has been shown to more readily demethylate trimethylated H3 Lys-4 (H3K4me3) and monomethylated H3 Lys4 (H3K4me1) consistent with its role in modulating the histone code. This protein is a highly conserved, constitutive nucleolar component that shows a dual localization pattern with strong enrichment in the granular part of nucleoli and in distinct nucleoplasmic entities.
Product Information
Format
Affinity Purified
Control
A431 cell lysate
Presentation
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
Detect NO66 using this rabbit polyclonal antibody, Anti-Histone lysine demethylase NO66 Antibody validated for use in western blotting.
Key Applications
Western Blotting
Biological Information
Immunogen
KLH-conjugated linear peptide corresponding to human Histone lysine demethylase NO66 near the N-terminus.
Epitope
Near N-terminus
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Rabbit
Specificity
This antibody recognizes Histone lysine demethylase NO66 near the N-terminus.
Species Reactivity
Human
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NP_078920
Gene Symbol
NO66
C14orf169
MAPJD
Purification Method
Antigen Affinity Purified
UniProt Number
Q9H6W3
Molecular Weight
~66 kDa observed
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in A431 cell lysate.
Western Blotting Analysis: 2.0 µg/mL of this antibody detected Histone lysine demethylase NO66 in 10 µg of A431 cell lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
