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Millipore Anti-Myb Binding Protein 1a Antibody Is A Highly Specific Rabbit Polyclonal Antibody, That Targets Myb-Binding Protein 1a & Has Been Tested In Western Blotting & Icc. - Mill (Additional S&H or Hazmat Fees May Apply)
Myb-binding protein 1A (MYBBP1A) interacts with sequence specific DNA-binding proteins in order to activate or repress transcription. Transcriptional repression via Myb-binding protein 1A is thought to be mediated by histone deacetylase activity (HDAC activity).
Product Information
Format
Serum
Control
A431 cell lysate
Presentation
Rabbit polyclonal serum with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
Anti-Myb Binding Protein 1A Antibody is a highly specific rabbit polyclonal antibody, that targets Myb-binding protein 1A & has been tested in western blotting & ICC.
Key Applications
Western Blotting
Immunocytochemistry
Chromatin Immunoprecipitation (ChIP)
Application Notes
Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected Myb Binding Protein 1A in diploid human lung embryonic fibroblasts (Prof. Atilla Nemeth, University of Regensburg, Germany.).
Immunocytochemistry Analysis: A representative lot from an independent laboratory detected Myb Binding Protein 1A in HeLa cells (Hochstatter, J., et Al. (2012). J Biol Chem. 287(29):24365-24377.).
Chromatin Immunoprecipitation (ChIP) Analysis: A representative lot from an independent laboratory immunoprecipitated Myb Binding Protein 1A in ChIP (Hochstatter, J., et Al. (2012). J Biol Chem. 287(29):24365-24377.).
Biological Information
Immunogen
GST-tagged recombinant protein corresponding to human Myb Binding Protein 1A.
Host
Rabbit
Specificity
This antibody detects the full length and cleaved forms of Myb Binding Protein 1A.
Species Reactivity
Human
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NP_001099008
Gene Symbol
MYBBP1A
P160
Purification Method
Unpurified
UniProt Number
Q9BQG0
Molecular Weight
~160 kDa observed. Uncharacterized band(s) may be observed in some cell lysates. The full length of this protein is observed at ~160 kDa; however, it is proteolytically cleaved into ~140 kDa and ~67 kDa fragments (Hochstatter, J., et Al. (2012). J Biol Chem. 287(29):24365-24377.; Mori, S., et Al. (2012). PLoS One. 7(10):e39723.).
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in A431 cell lysate.
Western Blotting Analyis: A 1:1,000 dilution from a representative lot detected Myb Binding Protein 1A in 10 µg of A431 cell lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
