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Millipore Anti-Slamf2 (Cd48 Antibody) Is A Highly Specific Rabbit Polyclonal Antibody, That Targets Cd48 & Has Been Tested In Western Blotting. - Mill (Additional S&H or Hazmat Fees May Apply)
Signaling lymphocytic activation molecule family member 2
CD48
BCM
BLAST1
MEM-102
CD48 antigen
B-lymphocyte activation marker BLAST-1
BCM1 surface antigen
Leukocyte antigen MEM-102
SLAMF
Background Information
The signaling lymphocyte-activation molecule family member 2 (SLAMF2), also known as CD48, is a GPI-anchored protein that exists as both a soluble and membrane-associated form and is expressed in almost all leukocyte populations particularly in mitogen-stimulated human lymphocytes. SLAMF2 is a high-affinity ligand for SLAMF4, also known as 2B4, as well as a low-affinity ligand for CD2, and can thus can stimulate cells expressing these receptors. It has been shown to be an IL-3-induced activating receptor on eosinophils and is likely to be involved in promoting allergic inflammation. SLAMF2 is also thought to be involved in the IL-18/IL-18R signaling cascade in T and natural killer cells to produce interferon-gamma.
Product Information
Format
Affinity Purified
Control
Rat lung tissue lysate
Presentation
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality Level
MQ100
Applications
Application
Anti-SLAMF2 (CD48 Antibody) is a highly specific rabbit polyclonal antibody, that targets CD48 & has been tested in western blotting.
Key Applications
Western Blotting
Biological Information
Immunogen
KLH-conjugated linear peptide corresponding to human SLAMF2.
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Rabbit
Species Reactivity
Rat
Species Reactivity Note
Demonstrated to react with Rat. Predicted to react with Human based on immunogen design.
Antibody Type
Polyclonal Antibody
Gene Symbol
CD48
SLAMF2
BCM1
Purification Method
Antigen Affinity Purified
UniProt Number
P09326
Molecular Weight
~17 and ~28 kDa observed
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in rat lung tissue lysate.
Western Blotting Analysis: 2 µg/mL of this antibody detected SLAMF2 in 15 µg of rat lung tissue lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
