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Millipore Detect Stromal Interaction Molecule 2 Using This Rabbit Polyclonal Antibody, Anti-Stim2 Antibody Validated For Use In Western Blotting, Ihc (Paraffin) & Immunofluorescence. - Mill (Additional S&H or Hazmat Fees May Apply)
Stromal interaction molecule 2 (STIM2) plays an important role in mediating store-operated Ca2+ entry (SOCE), a Ca2+ influx following depletion of intracellular Ca2+ stores. It inhibits STIM1-mediated store-operated Ca++ entry; however, STIM2 can form complexes with STIM1. This suggests that STIM1 and STIM2 may play a coordinated role in controlling Ca++ entry. STIM2 is expressed in all tissues and tumor cell lines examined.
Product Information
Format
Affinity Purified
Control
A-20 cell lysate
Presentation
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality Level
MQ100
Applications
Application
Detect Stromal interaction molecule 2 using this rabbit polyclonal antibody, Anti-STIM2 Antibody validated for use in western blotting, IHC (Paraffin) & Immunofluorescence.
Key Applications
Western Blotting
Immunohistochemistry (Paraffin)
Immunofluorescence
Application Notes
Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected STIM2 in human spleen tissue.
Immunofluorescence Analysis: 20 μg/mL from a representative lot detected STIM2 in human spleen cells.
Biological Information
Immunogen
KLH-conjugated linear peptide corresponding to the intermediate domain of human STIM2.
Epitope
Intermediate domain
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Rabbit
Specificity
This antibody recognizes the intermediate domain of STIM2.
Species Reactivity
Human
Mouse
Antibody Type
Polyclonal Antibody
Gene Symbol
STIM2
Purification Method
Antigen Affinity Purified
UniProt Number
Q9P246
Molecular Weight
~98 kDa observed
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in A-20 cell lysate.
Western Blotting Analysis: 2 µg/mL of this antibody detected STIM2 in 15 µg of A-20 cell lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
