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Millipore This Il-12 Alpha Antibody Is Validated For Use In Wb & Ihc For The Detection Of The Il-12 Alpha Protein. - Mill (Additional S&H or Hazmat Fees May Apply)
Interleukin-12 alpha (IL-12A) is also known as Cytotoxic lymphocyte maturation factor 35 kDa subunit (CLMF p35), IL-12 subunit p35, or NK cell stimulatory factor chain 1 (NKSF-1). IL-12A is a cytokine that, along with IL12B, forms a disulfide-linked heterodimer interleukin IL-12. IL-12 alpha functions as a regulator of T cell mediated cytotoxicity, interferon-gamma production, lymphocyte proliferation and activation of natural killer cells.
Product Information
Format
Affinity Purified
Control
Human lymph node tissue lysate
Presentation
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mm NaCl with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
This IL-12 alpha antibody is validated for use in WB & IHC for the detection of the IL-12 alpha protein.
Key Applications
Western Blotting
Immunohistochemistry (Paraffin)
Application Notes
Immunohistochemistry Analysis: A 1:16,000-32,000 dilution from a representative lot detected IL-12 alpha in human tonsil and human brain tissue.
Biological Information
Immunogen
KLH-conjugated linear peptide corresponding to the near C-terminus of human IL-12 alpha.
Epitope
Near C-terminus
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Rabbit
Specificity
This antibody recognizes the near C-terminus of IL-12 alpha
Species Reactivity
Human
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NP_000873
Gene Symbol
IL12A
NKSF1
Purification Method
Affinity Purfied
UniProt Number
P29459
Molecular Weight
~25 kDa observed
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in human lymph node tissue lysate.
Western Blotting Analysis: 0.2 µg/mL of this antibody detected IL-12 alpha in 10 µg of human lymph node tissue lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
