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Millipore Anti-Cx3cl1 Antibody Is A Highly Specific Rabbit Polyclonal Antibody, That Targets Cx3cl1 & Has Been Tested In Western Blotting. - Mill (Additional S&H or Hazmat Fees May Apply)
C-X3-C motif chemokine 1 (CX3CL1), also known as CX3C membrane-anchored chemokine, Neurotactin (NTT), Small-inducible cytokine D1 (SCYD1), and Fractalkine (FKN), is a CX3C chemokine known to induce adhesion and migration of leukocytes. Recent studies have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-alpha in activated microglia and neuronal cells, and it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Other evidence suggests that CX3CL1 may play a role in regulating leukocyte adhesion and migration processes at the endothelium. Additionally, CX3CL1 is implied to inhibit CX3CR1, which is a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection. CX3CL1 is expressed in small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas.
Product Information
Format
Affinity Purified
Control
C2C12 cell lysate
Presentation
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality Level
MQ100
Applications
Application
Anti-CX3CL1 Antibody is a highly specific rabbit polyclonal antibody, that targets CX3CL1 & has been tested in western blotting.
Key Applications
Western Blotting
Biological Information
Immunogen
KLH-conjugated linear peptide corresponding to human CX3CL1.
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Rabbit
Species Reactivity
Mouse
Species Reactivity Note
Demonstrated to react with Mouse. Predicted to react with Human based on immunogen design.
Antibody Type
Polyclonal Antibody
Gene Symbol
CX3CL1
Purification Method
Antigen Affinity Purified
UniProt Number
P78423
Molecular Weight
~50 kDa observed.
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in C2C12 cell lysate.
Western Blotting Analysis: 2 µg/mL of this antibody detected CX3CL1 in 15 µg of C2C12 cell lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.