The store will not work correctly when cookies are disabled.
We use cookies to make your experience better.To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
NETA ALERT: Due to inclement weather our offices are closed today, Monday Feb. 23. We will not be shipping orders.
Yeast VH1-related phosphatase (YVH1), also known as “dual specificity protein phosphatase 12” (DUSP12) is a ubiquitous phosphatase, with relatively high levels of expression in the ovary, testis, spleen, and peripheral blood leukocytes. YVH1 primarily removes phosphate groups from phosphorylated serine, threonine, and tyrosine residues in its target substrates. However, YVH1 also contains a zinc-binding domain which may enable it to interact with other proteins involved in cell growth, cell survival, and cell cycle progression. YVH1 may also be involved in the assembly of ribosomes, and in the biogenesis of the 60S ribosomal subunit. It can be targeted to different subcellular locations by phosphorylation of its Ser335 residue located in the zinc-binding domain.
Product Information
Format
Affinity Purified
Control
HeLa cells
Presentation
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
Anti-YVH1 Antibody is an antibody against YVH1 for use in Western Blotting.
Key Applications
Western Blotting
Application Notes
Western Blot Analysis: A representative lot detected YVH1 in 10 µg of Jurkat cell lysate.
Biological Information
Immunogen
GST-tagged recombinant protein corresponding to human YVH1.
Host
Rabbit
Species Reactivity
Human
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NP_009171
Gene Symbol
DUSP12
Purification Method
Affinity Purfied
UniProt Number
Q9UNI6
Molecular Weight
~38 kDa observed. An uncharacterized band at ~36 kDa may be observed in some cell lysates.
Product Usage Statements
Quality Assurance
Evaluated by Western Blot in HeLa cells.
Western Blot Analysis: A 1:500 dilution of this antibody detected YVH1 in 10 µg of HeLa cell lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
