The store will not work correctly when cookies are disabled.
We use cookies to make your experience better.To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
NETA ALERT: Due to inclement weather our offices are closed today, Monday Feb. 23. We will not be shipping orders.
Claudin-11 (CLDN11; or Oligodendrocyte-specific protein) is expressed in Sertoli cells of the testis. It is involved in the formation of tight junctions, which is required for spermatogenesis. Previous studies have indicated that claudin-11 may prevent the progression of bladder cancer by blocking cell invasion and metastatis.
Product Information
Format
Affinity Purified
Control
Human brain tissue lysate
Presentation
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
Anti-Claudin-11 Antibody is an antibody against Claudin-11 for use in Western Blotting.
Key Applications
Western Blotting
Application Notes
Western Blot Analysis: 1 µg/mL from a representative lot detected Claudin-11 in human kidney tissue lysate.
Western Blot Analysis: 2 µg/mL from a representative lot detected Claudin-11 in human testis tissue lysate.
Biological Information
Immunogen
KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Claudin-11.
Epitope
Cytoplasmic domain
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Rabbit
Specificity
This antibody recognizes the cytoplasmic domain of Claudin-11.
Species Reactivity
Human
Species Reactivity Note
Demonstrated to react with Human. Predicted to react with Chimpanzee based on 100% sequence homology. Other homologies: Mouse and Rat (93% sequence homology).
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NP_005593
Gene Symbol
CLDN11
OSP
OTM
Purification Method
Affinity Purfied
UniProt Number
O75508
Molecular Weight
~22 kDa observed. An uncharacterized band may be observed at ~60 kDa in some tissue lysates.
Product Usage Statements
Quality Assurance
Evaluated by Western Blot in human brain tissue lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected Claudin-11 in 10 µg of human brain tissue lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
