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Millipore Anti-Epithelial Specific Antigen Antibody, Clone Vu-1d9
Millipore Anti-Epithelial Specific Antigen Antibody, Clone Vu-1d9
List Price$358.40Your Price$358.40
Millipore Anti-Epithelial Specific Antigen Antibody, Clone Vu-1d9 Is A Highly Specific Mouse Monoclonal Antibody, That Targets Epithelial Cell Marker & Has Been Tested In Western Blotting, Icc & Ihc. - Mill (Additional S&H or Hazmat Fees May Apply)
Anti-Epithelial Specific Antigen Antibody, clone VU-1D9
Alternate Names
Epithelial cell adhesion molecule
Ep-CAM
Adenocarcinoma-associated antigen
Cell surface glycoprotein Trop-1
Epithelial cell surface antigen
Epithelial glycoprotein
EGP
Epithelial glycoprotein 314
EGP314
hEGP314
KS 1/4 antigen
KSA
Major gastrointestinal tumor-associated protein GA733-2
Tumor-associated calcium signal transducer 1
CD326
Background Information
Epithelial specific antigen, also known as epithelial cell adhesion molecule (Ep-CAM) and epithelial glycoprotein (EGP), may act as an interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Epithelial specific antigen plays a role in embryonic stem cells proliferation and differentiation, and up-regulates the expression of FABP5, MYC, and cyclins A and E. Epithelial specific antigen is highly and selectively expressed by undifferentiated embryonic stem cells (ESCs). Protein levels rapidly diminish as soon as ESCs differentiate. Also expressed in most epithelial cell membranes and on the surface of adenocarcinoma.
Product Information
Format
Purified
Control
MCF7 cell lyasate
Presentation
Purified mouse monoclonal IgG1κ in buffer containing PBS with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
Anti-Epithelial Specific Antigen Antibody, clone VU-1D9 is a highly specific mouse monoclonal antibody, that targets Epithelial Cell Marker & has been tested in western blotting, ICC & IHC.
Key Applications
Western Blotting
Immunocytochemistry
Immunohistochemistry
Application Notes
Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected Epithelial Specific Antigen in A431 cells.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Epithelial Specific Antigen in human prostate adenocarcinoma cells.
Biological Information
Immunogen
NCI-H69 whole cells
Clone
VU-1D9
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Mouse
Isotype
IgG1κ
Species Reactivity
Human
Antibody Type
Monoclonal Antibody
Entrez Gene Number
NP_002345
Gene Symbol
EPCAM
GA733-2
M1S2
M4S1
MIC18
TACSTD1
TROP1
Purification Method
Protein G Purified
UniProt Number
P16422
Molecular Weight
~40 kDa observed. The calculated molecular weight of this protein is 35 kDa; however, this protein will run higher due to glycosylation.
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in MCF7 cell lyate.
Western Blotting Analysis: 1 µg/mL of this antibody detected Epithelial Specific Antigen in 10 µg of MCF7 cell lyate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.