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Millipore Detect Cd19 Using This Milli-Mark Anti-Cd19 -Fitc Antibody, Clone Hd37 Validated For Use In Fc. - Mill (Additional S&H or Hazmat Fees May Apply)
CD19 is a 120 kDa transmembrane glycoprotein with a reduced MW of 95 kDa (Pezzutto, 1987; Sato, 1997). CD19 is a member of the immunoglobulin superfamily with two extracellular C2-type domains (Pezzutto, 1987), and it is a critical signal transduction molecule that regulates B lymphocyte development, activation, and differentiation (Sato, 1997). CD19 expression is restricted to B cells, being absent from T cells, monocytes, and granulocytes (Pezzutto, 1987). The CD19 antigen appears early during B cell maturation, probably at late pro-B cell stage around the time of Ig heavy chain rearrangement. It then persists during all stages of B cell maturation and is lost upon terminal differentiation to plasma cells (Pezzutto, 1987).
Product Information
Format
FITC
Control
Human Lymphocytes
Presentation
Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2
Quality Level
MQ100
Applications
Application
Detect CD19 using this Milli-Mark Anti-CD19 -FITC Antibody, clone HD37 validated for use in FC.
Key Applications
Flow Cytometry
Biological Information
Immunogen
Hairy cell leukemia cells
Clone
HD37
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Mouse
Specificity
Antibody recognizes Human CD19.
Isotype
IgG1κ
Species Reactivity
Human
Antibody Type
Monoclonal Antibody
Entrez Gene Number
NP_001761.3
Purification Method
Protein A Purfied
UniProt Number
P15391
Molecular Weight
120kDa (Pezzutto, 1987; Sato, 1997)
Product Usage Statements
Quality Assurance
Evaluated by flow cytometry using Human Lymphocytes
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.
