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Millipore Transforming Growth Factor-Beta2 Protein, Recombinant Human
Millipore Transforming Growth Factor-Beta2 Protein, Recombinant Human
List Price$426.19Your Price$426.19
Millipore Transforming Growth Factor-Beta2 (Tgf-Beta2) Is A Member Of A Superfamily Of Homologous, Disulfide-Linked, Homodimeric Proteins That Regulate The Proliferation & Differentiation Of Normal & Tr - Mill (Additional S&H or Hazmat Fees May Apply)
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Key Specifications Table
Key Applications
Species
Source
Purity
CULT
Human
Baculovirus infected High-5 cells
Greater than 95% by SDS-PAGE. Endotoxin level is less than 0.1 ng per μg (1EU/ug) of TGF-Beta2.
Description
Catalogue Number
GF113
Brand Family
Chemicon®
Trade Name
Chemicon
Description
Transforming Growth Factor-β2 Protein, Recombinant human
Overview
Transforming Growth Factor- beta2 (TGF-beta2) is a member of a superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation and differentiation of normal and transformed cells. Human TGF-beta2 is a 25.0 kDa protein with each subunit containing 112 amino acid residues.
Alternate Names
TGF-beta2
Product Information
Presentation
Lyophilized from Sodium Citrate, pH 3.5.
Quality Level
MQ100
Applications
Application
Transforming Growth Factor-beta2 (TGF-beta2) is a member of a superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation & differentiation of normal & transformed cells.
Key Applications
Cell Culture
Biological Information
Purity
Greater than 95% by SDS-PAGE. Endotoxin level is less than 0.1 ng per μg (1EU/ug) of TGF-Beta2.
Source
Baculovirus infected High-5 cells
Specific Activity
Determined by its ability to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells. The ED(50) was found to be <=0.2ng/ml, corresponding to a specific activity of >=5 x 10e6 units/mg.
Entrez Gene Number
NM_003238.1
Gene Symbol
TGFB2
Polyergin
G-TSF
TGF-beta-2
MGC116892
TGF-beta2
Cetermin
UniProt Number
P61812
UniProt Summary
FUNCTION: SwissProt: P61812 # TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth. SIZE: 414 amino acids; 47748 Da SUBUNIT: Homodimer; disulfide-linked. SUBCELLULAR LOCATION: Secreted. DISEASE: SwissProt: P61812 # A chromosomal aberration involving TGFB2 is found in a family with Peters anomaly [MIM:604229]. Translocation t(1;7)(q41;p21) with HDAC9. Peters anomaly consists of a central corneal leukoma, absence of the posterior corneal stroma and Descemet membrane, and a variable degree of iris and lenticular attachments to the central aspect of the posterior cornea. SIMILARITY: SwissProt: P61812 ## Belongs to the TGF-beta family.
Stem Cell Type
Mesenchymal Stem Cells
Product Usage Statements
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
The lyophilized powder is stable for a few weeks at room temperature, but best stored at -20°C. Reconstitute with water to a concentration of 50 μg/ml (e.g., 5 μg/100 μl), this will yield a solution of 1 mM citrate buffer pH 3.5 This solution can then be stored at room temperature or at 2-8ºC for 1 month. It is recommended that further dilutions be made into PBS containing 2 mg/ml albumin and stored at -20ºC. Reconstituted human TGF-beta2 should be stored in undiluted aliquots at -20°C for at least 2 months. Avoid repeated freeze/thaw cycles.
