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Millipore Anti-Calcitonin Gene Related Peptide Antibody, Alpha Hcgrp
Millipore Anti-Calcitonin Gene Related Peptide Antibody, Alpha Hcgrp
List Price$759.36Your Price$759.36
Millipore Anti-Calcitonin Gene Related Peptide Antibody, Α Hcgrp A.A. 28-37, Clone Cd8 Is An Antibody Against Calcitonin Gene Related Peptide For Use In Elisa, Ih. - Mill (Additional S&H or Hazmat Fees May Apply)
Anti-Calcitonin Gene Related Peptide Antibody, α hCGRP a.a. 28-37, clone CD8 is an antibody against Calcitonin Gene Related Peptide for use in ELISA, IH.
Key Applications
ELISA
Immunohistochemistry
Application Notes
Immunohistochemistry at 1:200-1:400. Antibody not reactive on formalin fixed tissues. 4% PFA frozen tissues preferred. Immersion (2 hours) or perfused (pH7.4); Blocking in PBS with 3% BSA or NGS containing 0.1% triton X-100 is advised. Primary antibody should be diluted only in PBS with no detergent or blocking compounds.
ELISA: against BSA-conjugated alpha CGRP peptide.
Optimal working dilutions to be determined by end user.
Biological Information
Immunogen
A terminal fragment of hCGRP coupled to BSA with glutaraldehyde.
Epitope
alpha hCGRP a.a. 28-37
Clone
CD8
Host
Mouse
Specificity
Highly specific for CGRP and does not cross-react with other amino acids.
Isotype
IgG1
Species Reactivity
Guinea Pig
Human
Antibody Type
Monoclonal Antibody
Entrez Gene Number
NM_001033952.1
NM_001033953.1
NM_001741.2
Entrez Gene Summary
Calcitonin is a peptide hormone synthesized by the parafollicular cells of the thyroid. It causes reduction in serum calcium, an effect opposite to that of parathyroid hormone (PTH; MIM 168450).[supplied by OMIM]
Gene Symbol
CALCA
CGRP-I
katacalcin
KC
CALC1
CGRP
MGC126648
calcitonin
CT
CGRP1
Non-Reactive Species
Rat
UniProt Number
P01258
UniProt Summary
FUNCTION: SwissProt: P01258 # Katacalcin is a potent plasma calcium-lowering peptide.| P06881 # CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP. SIZE: 141 amino acids; 15467 Da SUBCELLULAR LOCATION: Secreted. DOMAIN: SwissProt: P01258 SIMILARITY: SwissProt: P01258 ## Belongs to the calcitonin family.| P06881 ## Belongs to the calcitonin family.
Product Usage Statements
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
Maintain refrigerated at 2-8°C for up to 12 months.
