Special Offers
100% Performance Guaranteed
Key Specifications Table
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| H, Po, Fe | ELISA, WB, IH(P) | M | Purified | Monoclonal Antibody |
| Description | |
|---|---|
| Catalogue Number | MAB335 |
| Brand Family | Chemicon® |
| Trade Name |
|
| Description | Anti-Synaptobrevin Antibody, clone SP11 |
| Alternate Names |
|
| Product Information | |
|---|---|
| Format | Purified |
| Presentation | Liquid in 0.02 MPB and 0.25M NaCl, PH 7.6 with 0.1% sodium azide. |
| Quality Level | MQ100 |
| Applications | |
|---|---|
| Application | This Anti-Synaptobrevin Antibody, clone SP11 is validated for use in ELISA, WB, IH(P) for the detection of Synaptobrevin. |
| Key Applications |
|
| Application Notes | Immunohistochemistry at 1:100-1:200 Formalin fixed (fixed <4 weeks), paraffin embedded Frozen 4% Paraformaldehyde Western blotting at 1:100-1:1,000. ELISA at 1:500 Optimal working dilutions must be determined by the end user. |
| Biological Information | |
|---|---|
| Immunogen | Crude synaptic immunoprecipitate (Human) |
| Clone | SP11 |
| Host | Mouse |
| Specificity | Synaptobrevin [VAMP], 16kDa protein. Not reactive with bacterially expressed fusion protein. |
| Isotype | IgG1 |
| Species Reactivity |
|
| Antibody Type | Monoclonal Antibody |
| Entrez Gene Number |
|
| Entrez Gene Summary | Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. VAMP1 is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Multiple alternative splice variants that encode proteins with alternative carboxy ends have been described, but the full-length nature of some variants has not been defined. |
| Gene Symbol |
|
| Non-Reactive Species |
|
| UniProt Number |
|
| UniProt Summary | FUNCTION: SwissProt: P23763 # Involved in the targeting and/or fusion of transport vesicles to their target membrane. SIZE: 118 amino acids; 12902 Da SUBUNIT: Interacts with VAPA and VAPB. SUBCELLULAR LOCATION: Isoform 1: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein (By similarity). & Isoform 2: Cytoplasmic vesicle membrane; Single-pass type IV membrane protein (By similarity). & Isoform 3: Mitochondrion outer membrane; Single-pass type IV membrane protein. TISSUE SPECIFICITY: Nervous system, skeletal muscle and adipose tissue. SIMILARITY: SwissProt: P23763 ## Belongs to the synaptobrevin family. & Contains 1 v-SNARE coiled-coil homology domain. |
| Product Usage Statements | |
|---|---|
| Usage Statement |
|
| Storage and Shipping Information | |
|---|---|
| Storage Conditions | Maintain at 2-8°C in undiluted aliquots for up to 12 months. |
| Packaging Information | |
|---|---|
| Material Size | 100 µL |