The store will not work correctly when cookies are disabled.
We use cookies to make your experience better.To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
NETA ALERT: Due to inclement weather our offices are closed today, Monday Feb. 23. We will not be shipping orders.
Millipore This Anti-Dppa-2 Antibody, Clone 6c1.2, Alexa Fluor 488 Conjugate Is Validated For Use In Icc For The Detection Of Dppa-2. - Mill (Additional S&H or Hazmat Fees May Apply)
Pluripotent embryonic stem cell-related gene 1 protein
developmental pluripotency associated 2
Background Information
DPPA-2 (developmental pluripotency associated-2) is a novel Oct-4-related protein that is localized to the nucleus of mouse fetal germ cells. DPPA-2 has binding sites for both POU and Sox-2 protein domains and is expressed primarily in the developing germ line following gastrulation. These associations suggest that this protein participates in a very strong supportive role in maintaining cell pluripotentiality. In addition to its role as a pluripotency marker, more recent research using cancer cells suggests that DPPA-2 may also act as an embryo-cancer antigen—pointing to the presence of abnormal cell growth and the formation of cancerous cells.
Product Information
Format
AlexaFluor®488
Control
Mouse Embryonic Stem Cells (SCR012).
Presentation
Purified mouse monoclonal IgG2aλ supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
This Anti-DPPA-2 Antibody, clone 6C1.2, Alexa Fluor 488 conjugate is validated for use in ICC for the detection of DPPA-2.
Key Applications
Immunocytochemistry
Biological Information
Immunogen
recombinant protein corresponding to mouse DPPA-2.
Clone
6C1.2
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Mouse
Species Reactivity
Mouse
Antibody Type
Monoclonal Antibody
Entrez Gene Number
NP_082891
Gene Symbol
PESCRG1
Purification Method
Protein G Purified
UniProt Number
Q9CWH0
Molecular Weight
~30 kDa observed
Product Usage Statements
Quality Assurance
Evaluated by Immunocytochemistry in Mouse Embryonic Stem Cells (SCR012). Immunocytochemsitry Analysis: A 1:100 dilution of this antibody detected SOX-2 in Mouse Embryonic Stem Cells (SCR012).
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
Maintain refrigerated at 2-8ºC protected from light in undiluted aliquots for up to 6 months from date of receipt.
