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Millipore This Anti-Oxytocin Antibody, Clone 4g11 Is Validated For Use In Elisa, Ih For The Detection Of Oxytocin. - Mill (Additional S&H or Hazmat Fees May Apply)
This Anti-Oxytocin Antibody, clone 4G11 is validated for use in ELISA, IH for the detection of Oxytocin.
Key Applications
ELISA
Immunohistochemistry
Application Notes
Immunohistochemistry on 4% paraformaldehyde fixed frozen tissue: 1:5,000-1:10,000.
ELISA: 1:1,000,000
Optimal working dilutions must be determined by the end user.
Biological Information
Immunogen
Oxytocin conjugated to thyroglobulin.
Clone
4G11
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Mouse
Specificity
Recognizes Oxytocin. No reactivity to arginine vasopressin, vasotocin or [Asu1,6,Arg8]-vasopressin by competitive ELISA.
Isotype
IgG1
Species Reactivity
Human
Rat
Antibody Type
Monoclonal Antibody
Entrez Gene Number
NM_000915.2
Entrez Gene Summary
There are two proteins encoded by this gene, oxytocin and neurophysin I. Oxytocin is posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.
Gene Symbol
OXT
MGC126890
MGC126892
OT
OT-NPI
Purification Method
Unpurified
UniProt Number
P01178
UniProt Summary
FUNCTION: SwissProt: P01178 # Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland. SIZE: 125 amino acids; 12722 Da SUBCELLULAR LOCATION: Secreted. SIMILARITY: SwissProt: P01178 ## Belongs to the vasopressin/oxytocin family.
Product Usage Statements
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
