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Millipore Detect The Snf2l Protein Using This Anti-Snf2l, Clone Snf 2c4 Validated For Use In Wb & Ihc. - Mill (Additional S&H or Hazmat Fees May Apply)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1
Background Information
Nucleosome-remodeling factor subunit SNF2L, also known as SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1 (SMARCA1), is the energy-transducing component of NURF (nucleosome-remodeling factor) and CERF (CECR2-containing-remodeling factor) complexes. These complexes facilitate the disruption of chromatin structure in an ATP-dependent manner. SNF2L potentiates neurite outgrowth, and may be involved in brain development by regulating En-1 and En-2 expression as well as in the development of luteal cells.
Product Information
Format
Purified
Control
HeLa cell lysate
Presentation
Purified rat monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
Detect the SNF2L protein using this Anti-SNF2L, clone SNF 2C4 validated for use in WB & IHC.
Key Applications
Western Blotting
Immunohistochemistry
Application Notes
Western Blot Analysis: A representative lot was used by an an independent laboratory to detect SNF2L in untransfected HeLa whole cell extracts, but demonstrated a loss of signal in HeLa whole cell extracts transfected with siRNA. (Eckey, M., et al. (2012). Mol Cell Biol. 32(13):2359-2371). Immunohistochemistry Analysis: A representative lot was used by an an independent laboratory to detect SNF2L in certain, normal human organ tissues. (Eckey, M., et al. (2012). Mol Cell Biol. 32(13):2359-2371).
Biological Information
Immunogen
GST-tagged recombinant protein corresponding to human SNF2L.
Clone
SNF 2C4
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Western Blot Analysis: 1.0 µg/mL of this antibody detected SNF2L in 10 µg of HeLa cell lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
