The store will not work correctly when cookies are disabled.
We use cookies to make your experience better.To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
NETA ALERT: Due to inclement weather our offices are closed today, Monday Feb. 23. We will not be shipping orders.
Millipore This Anti-Wbp2 Antibody, Clone 4c8h10 Is Validated For Use In Western Blotting And Immunoprecipitation And Immunocytochemistry And Immunohistochemistry For The Detection Of Wbp2. - Mill (Additional S&H or Hazmat Fees May Apply)
WBP2 is a protein-protein interacting protein that binds to the WW domain of YAP1, WWP1 and WWP2 proteins. WW domain-containing proteins are found in most cells and play important roles in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. They are also upregulated in many cancers. WBP2 also interacts with the ubiquitin ligase proteins belonging to the NEDD4 family and appears to assist in the regulation of targeting proteins to proteasomes or lysosomes. Also in WBP2 knockout mice, the mice display abnormal brainstem and hearing development, indicating an important role in development as well.
Product Information
Format
Purified
Presentation
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
This Anti-WBP2 Antibody, clone 4C8H10 is validated for use in Western Blotting and Immunoprecipitation and Immunocytochemistry and Immunohistochemistry for the detection of WBP2.
Key Applications
Western Blotting
Immunoprecipitation
Immunocytochemistry
Immunohistochemistry
Application Notes
Immunohistochemistry Analysis: A representative lot detected WBP2 in breast cancer tissue at 1.25 ug/ml Immunocytochemistry Analysis: A representative lot detected WBP2 in transfected HeLa cell fixed with 4% paraformaldehyde at 20 ug/ml Immunoprecipitation Analysis: A representative lot immunoprecipitated transfected V5-WBP2 from HeLa cell
Biological Information
Immunogen
GST-tagged full length recombinant protein corresponding to Human WBP2.
Clone
4C8H10
Concentration
Please refer to lot specific datasheet.
Host
Mouse
Isotype
IgG1κ
Species Reactivity
Human
Antibody Type
Monoclonal Antibody
Entrez Gene Number
NP_036610
Gene Symbol
WBP2
Purification Method
Protein G Purified
UniProt Number
Q969T9
Molecular Weight
~ 37 kDa observed
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in MDA-MB-231 cell lysate.
Western Blotting Analysis: 2.0 µg/mL of this antibody detected WBP2 in 10 µg of MDA-MB-231 cell lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
