Miltenyi Biotec Cd273 (Pd-L2) Antibody, Anti-Mouse, Vio Bright B515, Reafinity; 30 µg in 200 µL

Miltenyi Biotec Clone REA986 recognizes CD273, a member of the B7 family of protein ligands. CD273, along with another member of the B7 family (B7-H1) are ligands of T-cell receptor known as programmed death-1 (PD-1). Surface expression of B7-DC is restricted to dendritic cells (DCs) and activated or IFNγ-stimulated DCs and macrophages. CD273/PD-1 interaction is involved in inhibition of T-cell activation, however a co-stimulatory role of CD273, via interaction with receptor other then PD-1 is also reported. | Additional Information: Clone REA986 displays negligible binding to Fc receptors. - MLTY (Additional S&H or Hazmat Fees May Apply)