Miltenyi Biotec Ifn-A Antibody, Anti-Human, Pure, Reafinity; 100 µg in 100 µL

Miltenyi Biotec Type I interferons (IFNs), including IFN-a, are a family of cytokines that exert pleiotropic functions in the immune system. Besides its potent antiviral activity, IFN-a exerts a variety of immunomodulatory effects, including positive and negative regulation of its own production, regulation of IL-12 and IFN-γ production, promotion of natural killer (NK) cell cytotoxicity, activation and maturation of dendritic cells, and the promotion of B cell development towards plasma cells. IFN-a is expressed predominantly by CD123+CD11c-CD303 (BDCA2)+ plasmacytoid dendritic cells (pDCs). Clone REA1013 recognizes the majority of the IFN-a subtypes, including IFN-a2b. | Additional information: Clone REA1013 displays negligible binding to Fc receptors. - MLTY (Additional S&H or Hazmat Fees May Apply)