Miltenyi Biotec Cd197 (Ccr7) Antibody, Anti-Mouse, Apc, Reafinity; 30 µg in 200 µL

Miltenyi Biotec Clone REA685 recognizes the mouse CD197 (CCR7) antigen, a chemokine receptor for chemokines CCL19 and CCL21. CD197, like other chemokine receptors has seven transmembrane spanning domains and signals via g proteins. Expression of CD197 is found on semi-mature and mature dendritic cells (DCs), naive B and T cells, regulatory T (Treg) cells, a subpopulation of T cells called central memory T cells, and non-immune malignant cells. CD197 is involved in regulating homing of immune cells, immunity to pathogens, immune tolerance, development and function of Tregs, and manifestation of autoimmunity. | Additional information: Clone REA685 displays negligible binding to Fc receptors. | - MLTY (Additional S&H or Hazmat Fees May Apply)