Miltenyi Biotec Cd230 (Prp) Antibody, Anti-Human, PE, Reafinity; 30 Tests in 60 mL

Miltenyi Biotec Clone REA203 recognizes CD230, commonly known as the prion protein (PrP). The normal cellular PrP (PrPc) is a ubiquitously expressed glycosylphosphatidyl-inositol (GPI) anchored protein. Though the main function of PrPc remains unknown, it has been suggested that PrPc may play a role in copper regulation, antioxidant activity, intracellular signaling. PrPsc is the conformational isoform of PrPc with similar primary sequence but different tertiary structure and is associated with neurodegenerative diseases such as Creutzfeldt-Jakob disease in humans, bovine spongiform encephalopathy, and scrapie in sheeps. PrPsc is suggested to derive from PrPc in a posttranslational process which involves PrPc-PrPsc molecular interactions. | Additional information: Clone REA203 displays negligible binding to Fc receptors. | - MLTY (Additional S&H or Hazmat Fees May Apply)