Miltenyi Biotec Cd158e/K (Kir3dl1/Dl2) Antibody, Anti-Human, Pure, Reafinity; 100 µg in 100 µL

Miltenyi Biotec Clone REA970 recognizes the human CD158e (KIR3DL1) and CD158k (KIR3DL2) antigens, members of the killer immunoglobulin-like receptor (KIR) family which recognizes subsets of HLA alleles. The family of KIR contributes to the regulation of NK cell–mediated cytotoxicity. Expression is found mainly on CD56dimCD16+ natural killer (NK) cells but also on a subset of CD8+ T cells. They are monomeric receptors possessing high allelic polymorphism with either two or three Ig-like extracellular domains. According to the length of their cytoplasmic tail, KIRs can be subdivided in inhibitory KIRs and activating KIRs. | Additional information: Clone REA970 displays negligible binding to Fc receptors. - MLTY (Additional S&H or Hazmat Fees May Apply)