Miltenyi Biotec Cd321 (Jam1) Antibody, Anti-Human, Fitc, Reafinity; 100 Tests in 200 µL

Miltenyi Biotec Clone REA605 recognizes the human CD321 antigen, a cell-surface adhesion molecule, also known as JAM1 or JAMA. CD321 is a type I transmembrane glycoprotein belonging to the immunoglobin superfamily. It has two extracellular Ig-like domains, a transmembrane region and a short cytosolic tail. | CD321 is expressed on a variety of cell types: erythrocytes, leukocytes, platelets, as well as endothelial and epithelial cells. CD321 has different functions. It is a regulator of tight junction assembly in epithelia and acts as a receptor for reovirus. Furthermore CD321 binds integrin LFA1 and is involved in leukocyte transmigration. In addition, CD321 is a platelet receptor. | Additional information: Clone REA605 displays negligible binding to Fc receptors. - MLTY (Additional S&H or Hazmat Fees May Apply)