Miltenyi Biotec Ifn-A Antibody, Anti-Human, Fitc; 100 Tests in 200 µL

Miltenyi Biotec Type I interferons (IFNs), including IFN-a, are a family of cytokines that exert pleiotropic functions in the immune system. Besides its potent antiviral activity, IFN-a exerts a variety of immunomodulatory effects, including positive and negative regulation of its own production, regulation of IL-12 and IFN-γ production, promotion of natural killer (NK) cell cytotoxicity, activation and maturation of dendritic cells, and the promotion of B cell development towards plasma cells. IFN-a is expressed predominantly by CD123+CD11c-CD303 (BDCA2)+ plasmacytoid dendritic cells (pDCs). Clone LT27:295 recognizes the majority of the IFN-a subtypes, including IFN-a2b. - MLTY (Additional S&H or Hazmat Fees May Apply)