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GenScript Dnam-1/Cd226, His, Human; 100 μg
List Price $200.00 Your Price $200.00
GenScript Dnam-1/Cd226, His, Human - GSCRPT (Additional S&H or Hazmat Fees May Apply)
NETA PART: GSCRPT-Z03455-100
MFG.PART: Z03455-100
UNSPSC: 12352202
Manufacturer: GenScript USA Inc
Product Introduction
| Species | Human | ||||
| Protein Construction |
| ||||
| Purity | > 90% as analyzed by SDS-PAGE | ||||
| Endotoxin Level | < 1 EU/μg of protein by gel clotting method | ||||
| Biological Activity | DNAM-1/CD226, His, Human can bind with CHO-K1/aAPC/CD155 Clone by FACS analysis. | ||||
| Expression System | HEK 293 | ||||
| Apparent Molecular Weight | ~39.3 kDa, on SDS-PAGE under reducing conditions. | ||||
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS. | ||||
| Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml. | ||||
| Storage & Stability | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles. |
Background
| Target Background | CD226 (Cluster of Differentiation 226), also known as PTA1 (outdated term, platelet and T cell activation antigen 1)[5] or DNAM-1 (DNAX Accessory Molecule-1), is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. It is a member of the immunoglobulin superfamily. This protein is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. It is the cell surface receptor for NECTIN2 and its main ligands are CD112 and CD155. It stimulates T-cell proliferation and cytokine production, including that of IL-2, IL-5, IL-10, IL-13, and IFNγ upon ligand binding. |
| Synonyms | DNAM-1; DNAM1; PTA1; TLiSA1; CD226 molecule |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
| SKU | GSCRPT-Z03455-100 |
|---|---|
| Supplier Part Number | Z03455-100 |
| UM | EA |
| UNSPSC | 12352202 |
| Manufacturer | GenScript USA Inc |
| Temperature | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (examp |
| ProductLine | GSCRPT |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 7 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |