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GenScript Nectin-2/Cd112 Fc Chimera, Human; 100 μg
List Price $200.00 Your Price $200.00
GenScript Nectin-2/Cd112 Fc Chimera, Human - GSCRPT (Additional S&H or Hazmat Fees May Apply)
NETA PART: GSCRPT-Z03456-100
MFG.PART: Z03456-100
UNSPSC: 12352202
Manufacturer: GenScript USA Inc
Product Introduction
| Species | Human | ||||
| Protein Construction |
| ||||
| Purity | > 90% as analyzed by SDS-PAGE | ||||
| Endotoxin Level | < 1 EU/μg of protein by gel clotting method | ||||
| Expression System | HEK 293 | ||||
| Apparent Molecular Weight | ~75.2 kDa, on SDS-PAGE under reducing conditions. | ||||
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS. | ||||
| Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml. | ||||
| Storage & Stability | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles. |
Background
| Target Background | Nectin-2, also known as CD112 (Cluster of Differentiation 226) and PVRL2 (Poliovirus receptor-related 2), is a human plasma membrane glycoprotein. This protein is a modulator of T-cell signaling and can be either a costimulator of T-cell function or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, it stimulates T-cell proliferation and cytokine production, including that of IL-2, IL-5, IL-10, IL-13, and IFNγ. It can also inhibit T-cell proliferation upon interaction with PVRIG. Nectin-2 also acts as a receptor for herpes simplex virus 1 (HHV-1) mutant Rid1, herpes simplex virus 1 (HHV-2) and pseudorabies virus (PRV). |
| Synonyms | NECTIN2; CD112; HVEB; PRR2; PVRR2; PVRL2; nectin cell adhesion molecule 2 |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
| SKU | GSCRPT-Z03456-100 |
|---|---|
| Supplier Part Number | Z03456-100 |
| UM | EA |
| UNSPSC | 12352202 |
| Manufacturer | GenScript USA Inc |
| Temperature | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (examp |
| ProductLine | GSCRPT |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 7 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |