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GenScript Sars-Cov-2 Spike Protein (S1, T19r, G142d, Del 156-157, R158g, L452r, T478k, D614g, P681r, His Tag); 1mg
List Price $2,100.00 Your Price $2,100.00
GenScript Sars-Cov-2 Spike Protein (S1, T19r, G142d, Del 156-157, R158g, L452r, T478k, D614g, P681r, His Tag) - GSCRPT (Additional S&H or Hazmat Fees May Apply)
NETA PART: GSCRPT-Z03612-1
MFG.PART: Z03612-1
UNSPSC: 12352202
Manufacturer: GenScript USA Inc
Product Introduction
| Species | SARS-CoV-2 | ||||
| Protein Construction | Expressed with the mutations of T19R, G142D, del 156-157, R158G, L452R, T478K, D614G, P681R.
| ||||
| Purity | > 90% as analyzed by SDS-PAGE | ||||
| Endotoxin Level | < 0.2 EU/μg of protein by gel clotting method | ||||
| Biological Activity | This protein is validated to bind with human ACE2 in functional ELISA assay. | ||||
| Expression System | CHO | ||||
| Theoretical Molecular Weight | 75.7 kDa | ||||
| Apparent Molecular Weight | ~112 kDa, on SDS-PAGE under reducing conditions. | ||||
| Formulation | Supplied as a solution in PBS, pH 7.4. | ||||
| Concentration | Please refer to the COA for the specific lot. | ||||
| Storage & Stability | Upon receiving, this product remains stable for up to 6 months at -20°C or below. Please avoid repeated freeze-thaw cycles. |
Background
| Target Background | SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. As of May 2021, three sublineages have been found. Despite its name, B.1.617.3 was the first sublineage of this variant to be detected, in October 2020 in India. This sublineage has remained relatively uncommon compared to the two other sublineages, B.1.617.1 (also known as variant Kappa) and B.1.617.2 (also known as variant Delta), both of which were first detected in December 2020. This variant has the double mutations E484Q and L452R in the spike proteins. Emerging research suggests the variant may be more transmissible than previously evolved ones. Whether the effectiveness of currently-deployed vaccines is affected remains under investigation. Moreover, the sublineage B.1.617.2 has been redesignated as "variant of concern" (VOC-21APR-02) in May 2021, which spreads more quickly than the original version of the virus. |
| Synonyms | Lineage B.1.617.2; VUI-21APR-02; variant Delta |
| References | 1. Emergence of a novel SARS-CoV-2 strain in Southern California, USA. 2. New California Variant May Be Driving Virus Surge There, Study Suggests. 3. Neutralization of SARS-CoV-2 Variants B.1.429 and B.1.351. 4. Tracking SARS-CoV-2 variants. |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
| SKU | GSCRPT-Z03612-1 |
|---|---|
| Supplier Part Number | Z03612-1 |
| UM | EA |
| UNSPSC | 12352202 |
| Manufacturer | GenScript USA Inc |
| Temperature | Upon receiving, this product remains stable for up to 6 months at -20°C or below. Please avoid repeated freeze-thaw cycles. |
| ProductLine | GSCRPT |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 7 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |