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GenScript Cs1/Cracc/Slamf7, His & Avi, Human; 100ug
List Price $200.00 Your Price $200.00
GenScript Cs1/Cracc/Slamf7, His & Avi, Human - GSCRPT (Additional S&H or Hazmat Fees May Apply)
NETA PART: GSCRPT-Z03649-100
MFG.PART: Z03649-100
UNSPSC: 12352202
Manufacturer: GenScript USA Inc
Product Introduction
| Species | Human | ||||||
| Protein Construction |
| ||||||
| Purity | > 95% as analyzed by SDS-PAGE > 95% as analyzed by HPLC | ||||||
| Endotoxin Level | ≤ 1 EU/μg of protein by LAL method | ||||||
| Biological Activity | Immobilized SLAMF7, His & Avi Tag at 1.0 ug/ml (100 ul/Well). Dose response curve for Elotuzumab with the EC50 of 42.6 ng/ml determined by ELISA. | ||||||
| Expression System | Expi293 | ||||||
| Apparent Molecular Weight | 40~50 kDa, on SDS-PAGE under reducing conditions. | ||||||
| Formulation | Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4. Normally 5 % trehalose is added as protectant before lyophilization. | ||||||
| Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. | ||||||
| Storage & Stability | Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Avoid repeated freeze-thaw cycles. |
Background
| Target Background | CD2-like receptor activating cytotoxic cells (CRACC), also known as CS1, novel Ly9, SLAMF7, and CD319, is a 65-75 kDa type I transmembrane glycoprotein in the SLAM subgroup of the CD2 family, a self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune responses. |
| Synonyms | CD319 antigen; CD319; 19A; CD2 subset 1; CD2-like receptor activating cytotoxic cells; CRACC; CRACCCD2-like receptor-activating cytotoxic cells; CS119A24 protein; Membrane protein FOAP-12; novel LY9 (lymphocyte antigen 9) like protein; Novel Ly9; Protein 19A; SLAM family member 7; SLAMF7; CS1 |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
| SKU | GSCRPT-Z03649-100 |
|---|---|
| Supplier Part Number | Z03649-100 |
| UM | EA |
| UNSPSC | 12352202 |
| Manufacturer | GenScript USA Inc |
| Temperature | Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Avoid repeated freeze-thaw cycles. |
| ProductLine | GSCRPT |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 7 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |