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Millipore The Endostatin Protein Is A Naturally Occurring 20 Kda Polypeptide Derived From The C-Terminal Portion Of Type Xviii Collagen. - Mill (Additional S&H or Hazmat Fees May Apply)
Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
Description
Catalogue Number
GF171
Description
Endostatin Protein, Human Recombinant
Alternate Names
Collagen Type XVIII
Collagen alpha-1 (XVIII)
Background Information
Endostatin is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen. It functions as an anti-angiogenic cytokine that is expressed in various organs with the highest levels in liver, lung and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant human Endostatin is a 20.2 kDa protein consisting 184 amino acid residues.
Product Information
Presentation
Product is filtered through a 0.2 micron filter before lyophilization.
Quality Level
MQ100
Applications
Application
The Endostatin protein is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen.
Biological Information
Purity
Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
Source
E. coli.
Cross Reactivity
None
UniProt Number
P39060
Product Usage Statements
Quality Assurance
Bioactivity assay: Measured by its ability to inhibit HUVEC migration.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
Store at -20°C for up to 6 months from date of receipt.
