Revvity HTRF Hman and Moe LC3B-II Detection Kit, 500 Aay Point

Revvity LC3 i a mammalian homolog of the yeat ATG8 rotein and i ditrited throghot mammalian tie and cltred cell. LC3 i a key comonent of the atohagy roce - a degradative rogram that maintain celllar homeotai.Dring atohagy, cytolamic comonent ch a cytoolic rotein and organelle are englfed y atohagoome Concrrently, a cytoolic form of LC3 (LC3-I) i conjgated to hohatidylethanolamine to form LC3-hohatidylethanolamine conjgate (LC3-II). Thi newly formed conjgate i recrited to atohagoomal memrane. The eqent fion of atohagoome with lyoome relt in the formation of atolyoome, and intra-atohagoomal comonent are degraded y lyoomal hydrolae. At the ame time, LC3-II within the atolyoomal lmen i degraded.The LC3-II level ha een fond to e roortional to atohagoome andance making LC3-II the mot olar marker of atohagy.-PEGSK(Additional S&H Or Hazmat Fees May Apply)