Revvity Alphalisa Surefire Ultra Human Phospho-C-Fos (Ser32) Detection Kit, 100 Assay Points

Revvity Protein c-Fo i encoded y the FOS gene, a roto-oncogene that i the hman homolog of the retroviral oncogene v-fo. The Activator Protein-1 (AP-1) comlex i formed when c-Fo and c-Jn form a heterodimer. Thi comlex ind DNA at ecific AP-1 ite in the romoter and enhancer region of target gene, converting extracelllar ignal into change in gene exreion. Additionally, ottranlational alteration roght on y hohorylation y vario kinae, ch a MAPK, CDC2, PKA, or PKC, reglate it activity. C-Fo lay an imortant role in nmero celllar fnction, inclding cell roliferation, differentiation, rvival, gene aociated with hyoxia, and ha een fond to e overexreed in a variety of cancer. The AlhaLISA SreFire Ultra Hman Phoho-c-FOS (Ser32) Detection Kit i a andwich immnoaay for the qantitative detection of hoho-c-FOS (Ser32) in celllar lyate, ing Alha Technology. Format:The HV (high volme) kit contain reagent to rn 100 well in 96-well format, ing a 60 &M;L reaction volme.The 500-oint kit contain enogh reagent to rn 500 well in 384-well format, ing a 20 &M;L reaction volme.The 10,000-oint kit contain enogh reagent to rn 10,000 well in 384-well format, ing a 20 &M;L reaction volme.The 50,000-oint kit contain enogh reagent to rn 50,000 well in 384-well format, ing a 20 &M;L reaction volme.AlhaLISA SreFire Ultra kit are comatile with:Cell and tie lyateAntiody modlatorBiotheraetic antiodieAlha SreFire kit can e ed for:Celllar kinae aayRecetor activation tdieScreening-PEGSK(Additional S&H Or Hazmat Fees May Apply)