Revvity Alphalisa Surefire Ultra Total P300 Detection Kit, 50,000 Assay Points

Revvity Histone acetyltransferase p300 is an acetyl transferase encoded by the ep300 gene with numerous aliases: p300, p300 hat, e1a-associated protein p300 (where e1a = adenovirus early region 1a), and ep300. P300 mediates histone 3 lysine 27 acetylation (h3k27ac) at regulatory elements such as enhancers and promoters. P300 is over-expressed in cancer cells and drug-resistant cancer cells, it activates oncogene transcription and induces cancer cell proliferation, survival, tumorigenesis, metastasis, immune evasion, and drug-resistance. The alphalisa surefire human total p300 detection kit is a sandwich immunoassay for the quantitative detection of total p300 in cellular lysates, using alpha technology. Formatsthe hv (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μl reaction volume. The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μl reaction volume. The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μl reaction volume. The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μl reaction volume. Alphalisa surefire ultra kits are compatible withcell and tissue lysatesantibody modulatorsbiotherapeutic antibodiesalpha surefire kits can be used forcellular kinase assaysreceptor activation studiesscreening - PEGSK (Additional S&H Or Hazmat Fees May Apply)