Cayman Ganglioside GD1b Polyclonal Antibody

Ganglioside g_D1b (Item No. ) is an acidic glycosphingolipid that contains two sialic acid residues linked to an inner galactose unit. It is a component of plasma membranes where it packs densely with cholesterol to form lipid microdomains that modulate both intra- and intercellular signaling events. The concentration of ganglioside g_D1b in human brain increases with age, constituting 7.85% of total sialic acid in the brain of 0- to 10-year-old subjects and 20.29% in 11- to 30-year-old subjects. Ganglioside g_D1b levels are positively correlated with pilocytic astrocytoma tumor grade, and g_D1b has been detected in various other gliomas, including primitive neuroectodermal tumors, glioblastomas, and anaplastic astrocytomas. Ganglioside g_D1b Polyclonal Antibody can be used for ELISA and TLC immunoblotting applications. [Matreya, LLC. Catalog No. 1964]

WARNING This product is not for human or veterinary use.