Cell Signaling Batf3 (E3k5h) Rabbit mAb

Name: Cell Signaling Batf3 (E3k5h) Rabbit mAb
SKU: CSIG-16484S
Price: 342.39 USD

List Price $342.39 Your Price $342.39

Cell Signaling Batf3 (E3k5h) Rabbit mAb - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-16484S

MFG.PART: 16484S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µl
Reactivity	H
Sensitivity	Endogenous
Molecular Weight (kDa)	18
Source/Isotype	Rabbit IgG
Application/Dilution	{Western Blotting: 1:1000, Immunoprecipitation: 1:200, Flow Cytometry (Fixed/Permeabilized): 1:800 - 1:1600}
Storage	Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	BATF3 (E3K5H) Rabbit mAb recognizes endogenous levels of total human BATF3 protein. This clone exhibits reactivity by western blot in cell lines transfected with a construct expressing Myc/DDK-tagged mouse BATF3 protein.
Species Reactivity	Human
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human BATF3 protein.
Background	BATF3 (Basic leucine zipper transcriptional factor ATF-like 3, p21SNFT) is a member of the basic leucine zipper family (1,2,5) which dimerizes with Jun proteins and represses activator protein-1 (AP-1) activity (1). BATF3 is required for development of conventional type 1 dendritic cells (cDC1s), which cross-present antigens in the context of MHC class I to naïve CD8+ T cells, priming them to become activated cytotoxic CD8+ T cells (2-4).

Specifications