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Cell Signaling Sars-Cov-2 Membrane Protein (E3v5h) Mouse mAb
List Price
$339.36
Your Price
$339.36
Cell Signaling Sars-Cov-2 Membrane Protein (E3v5h) Mouse mAb - CSIG (Additional S&H or Hazmat Fees May Apply)
NETA PART:
CSIG-32904S
MFG.PART:
32904S
UNSPSC:
12352203
Manufacturer:
Cell Signaling
| Size | 100 µl |
| Reactivity | Vir |
| Sensitivity | Endogenous |
| Molecular Weight (kDa) | 20-30 |
| Source/Isotype | Mouse IgG3 |
| Application/Dilution | {Western Blotting: 1:1000} |
| Storage | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody. |
| Specificity/Sensitivity | SARS-CoV-2 Membrane Protein (E3V5H) Mouse mAb recognizes endogenous levels of total SARS-CoV-2 membrane protein in infected cells. In some transfected models, a band of unknown origin, but not virus related, may be observed at approximately 50 kDa. |
| Species Reactivity | Virus |
| Source/Purification | Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala183 of SARS-CoV-2 membrane protein. |
| Background | The cause of the COVID-19 pandemic is a novel and highly pathogenic coronavirus, termed SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2). SARS-CoV-2 is a member of the Coronaviridae family of viruses (1). The genome of SARS-CoV-2 is relatively large and encodes up to 29 open reading frames (ORFs). These include ORF1a and ORF1b (further processed into 16 non-structural proteins), 9 accessory proteins, and 4 canonical structural proteins: spike (S), envelope (E), membrane (M), and nucleocapsid (N) (2). Membrane protein is transcribed and translated from nested subgenomic RNA of the SARS-CoV-2 genome. Interaction of the membrane protein with the viral nucleocapsid protein is thought to stabilize the RNA-protein complex in the virions (3). Membrane protein has also been suggested to interact with the viral spike protein, but the functional consequence of that interaction is currently unclear (4). |
| SKU | CSIG-32904S |
|---|---|
| Featured | No |
| Supplier Part Number | 32904S |
| UM | EA |
| UNSPSC | 12352203 |
| Manufacturer | Cell Signaling |
| MSDS URL | Click here |
| Temperature | -20C |
| CountryOfOrigin | United States |
| ProductLine | CSIG |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| ACT Ecolabel | No |