Cell Signaling Slc25a40 (E9c7y) Rabbit mAb

Name: Cell Signaling Slc25a40 (E9c7y) Rabbit mAb
SKU: CSIG-38244S
Price: 379.76 USD

List Price $379.76 Your Price $379.76

Cell Signaling Slc25a40 (E9c7y) Rabbit mAb - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-38244S

MFG.PART: 38244S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Size	100 µl
Reactivity	H
Sensitivity	Endogenous
Molecular Weight (kDa)	32
Source/Isotype	Rabbit IgG
Application/Dilution	{Western Blotting: 1:1000}
Storage	Supplied in 10 mm sodium HEPES (pH 7.5), 150 mm NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	SLC25A40 (E9C7Q) Rabbit mAb recognizes endogenous levels of total SLC25A40 protein.
Species Reactivity	Human
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Lys330 of human SLC25A40 protein.
Background	Members of the solute carrier 25 (SLC25) family transport molecules over the mitochondrial inner membrane (1,2). Mutations in these carriers often result in rare but severe pathologies (3). SLC25A39 and its paralogue SLC25A40 were found to be essential for mitochondrial import of glutathione, providing protection against oxidative stress and mitochondrial dysfunction (4,5). Changes in SLC25A39 and SLC25A40 expression were found in cholestasis-associated renal injury and LPS-induced inflammation (6).