Cell Signaling Epcam (E8q1z) Rabbit mAb (Mouse Preferred)

Name: Cell Signaling Epcam (E8q1z) Rabbit mAb (Mouse Preferred)
SKU: CSIG-42515S
Price: 354.51 USD

List Price $354.51 Your Price $354.51

Cell Signaling Epcam (E8q1z) Rabbit mAb (Mouse Preferred) - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-42515S

MFG.PART: 42515S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µl
Reactivity	H M R
Sensitivity	Endogenous
Molecular Weight (kDa)	35-45
Source/Isotype	Rabbit IgG
Application/Dilution	{Western Blotting: 1:1000, Immunoprecipitation: 1:50, Immunofluorescence (Frozen): 1:800, Immunofluorescence (Immunocytochemistry): 1:800}
Storage	Supplied in 10 mm sodium HEPES (pH 7.5), 150 mm NaCl, 100 µg/mL BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	EpCAM (E8Q1Z) Rabbit mAb recognizes endogenous levels of total EpCAM protein.
Species Reactivity	Human, Mouse, Rat
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Arg311 of mouse EpCAM protein.
Background	Epithelial cell adhesion and activating molecule (EpCAM/CD326) is a transmembrane glycoprotein that mediates Ca2+-independent, homophilic adhesions on the basolateral surface of most epithelial cells. EpCAM is not expressed in adult squamous epithelium, but it is highly expressed in adeno and squamous cell carcinomas (1). Research studies identified EpCAM as one of the first tumor-associated antigens, and it has long been a marker of epithelial and tumor tissue. Investigators have shown that EpCAM is highly expressed in cancer cells (reviewed in 2,3).

Specifications