Cell Signaling Cd15/Ssea1 (Mc480) Mouse mAb

Name: Cell Signaling Cd15/Ssea1 (Mc480) Mouse mAb
SKU: CSIG-4744S
Price: 351.48 USD

List Price $351.48 Your Price $351.48

Cell Signaling Cd15/Ssea1 (Mc480) Mouse mAb - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-4744S

MFG.PART: 4744S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Size	100 µl
Reactivity	H M
Sensitivity	Endogenous
Source/Isotype	Mouse IgM
Application/Dilution	{Immunohistochemistry (Paraffin): 1:100, Immunofluorescence (Immunocytochemistry): 1:1000, Flow Cytometry (Fixed/Permeabilized): 1:1600, Flow Cytometry (Live): 1:1600}
Storage	Supplied in 10 mm sodium HEPES (pH 7.5), 150 mm NaCl, 100 µg/mL BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.For a carrier free (BSA and azide free) version of this product see product #74180.
Specificity/Sensitivity	SSEA1 Antibody detects endogenous levels of SSEA1 antigen.
Species Reactivity	Human, Mouse
Source/Purification	Monoclonal antibody is produced by immunizing animals with F9 teratoma cells (X-irradiated).
Background	SSEA1 antibody detects a lactoseries oligosaccharide antigen that is expressed on the surface of mouse embryonal carcinoma and embryonic stem cells (1). This antigen is also found on early mouse embryos and both mouse and human germ cells, but is absent on human embryonic stem and carcinoma cells. Expression of SSEA1 in these human cell types increases upon differentiation, while on the mouse cell types differentiation leads to decreased expression (2).