Cell Signaling Nanog (D73g4) Xp Rabbit mAb (Chip Formulated)

Name: Cell Signaling Nanog (D73g4) Xp Rabbit mAb (Chip Formulated)
SKU: CSIG-5232S
Price: 387.84 USD

List Price $387.84 Your Price $387.84

Cell Signaling Nanog (D73g4) Xp Rabbit mAb (Chip Formulated) - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-5232S

MFG.PART: 5232S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Size	100 µl
Reactivity	H
Sensitivity	Endogenous
Source/Isotype	Rabbit IgG
Application/Dilution	{Chromatin IP: 1:50, Chromatin IP-seq: 1:50, CUT&RUN: 1:50}
Storage	Supplied in 10 mm sodium HEPES (pH 7.5), 150 mm NaCl, 100 µg/mL BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	Nanog (D73G4) XP® Rabbit mAb (ChIP Formulated) detects endogenous levels of total nanog protein.
Species Reactivity	Human
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to the amino terminus of human nanog protein.
Background	Nanog is a homeodomain-containing transcription factor that is essential for the maintenance of pluripotency and self renewal in embryonic stem cells (1). Nanog expression is controlled by a network of factors including Sox2 and the key pluripotency regulator Oct-4 (1). Recent advances in somatic cell reprogramming have utilized viral expression of combinations of transcription factors including nanog, Oct-4, Sox2, KLF4, c-Myc, and LIN28 (2,3).