Cell Signaling Egr1 (44d5) Rabbit mAb (BSA And Azide Free)

Name: Cell Signaling Egr1 (44d5) Rabbit mAb (BSA And Azide Free)
SKU: CSIG-54070SF
Price: 873.65 USD

List Price $873.65 Your Price $873.65

Cell Signaling Egr1 (44d5) Rabbit mAb (BSA And Azide Free) - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-54070SF

MFG.PART: 54070SF

UNSPSC: 12352203

Manufacturer: Cell Signaling

Size	100 µg
Reactivity	H M R
Sensitivity	Endogenous
Molecular Weight (kDa)	75
Source/Isotype	Rabbit IgG
Application/Dilution	{}
Storage	Supplied in 1X PBS, BSA and Azide Free.For standard formulation of this product see product #4154
Specificity/Sensitivity	EGR1 (44D5) Rabbit mAb (BSA and Azide Free) detects endogenous levels of total EGR1 protein.
Species Reactivity	Human, Mouse, Rat
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to the amino terminus of the sequence of human EGR1.
Background	EGR family members are transcriptional factors that contain three repetitive zinc finger DNA binding domains which bind to EGR response elements (ER) to regulate target gene expression (1). The expression of EGR family members is induced by growth factors, with EGR1 expression being induced by NGF (1,2). Increased EGR1 expression activates transcription of other signaling molecules, including CDK5 and tyrosine hydroxylase, and exerts long term effects on neural cell growth and differentiation (2,3).